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【文獻(xiàn)標(biāo)題】Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits

【作者】Xiaowei Zhang,Zhiwei Zhang,Yajuan Yang,et.al

【作者單位】天津醫(yī)科大學(xué)第二醫(yī)院(Second Hospital of Tianjin Medical University)

【文獻(xiàn)中引用產(chǎn)品】

兔胰高血糖素（Glucagon）ELISA試劑盒

兔8羥基脫氧鳥苷（8-OHdG）ELISA試劑盒

【關(guān)鍵詞】Dipeptidyl peptidase-4 inhibitors, Diabetic cardiomyopathy, Diabetes mellitus, Mitochondrial function, Mitochondrial biogenesis

【DOI】doi.org/10.1186/s12933-018-0803-z

【影響因子(IF)】9.5

【出版期刊】《BMC BIOLOGY》

【產(chǎn)品原文引用】

 Serum biochemical, infammatory oxidative stress measurements. Blood samples collected were used for serum biochemical examination, including fasting glucose, total cholesterol, triglyceride, low-density lipoprotein cholesterol (LDL-c), high density lipoprotein cholesterol (HDL-c) and creatinine level by full automatic biochemical analyzer. Fasting insulin and GLP-1 level were assessed using Rabbit Insulin ELISA Kit (Wuhan Huamei Biological Engineering Co., Ltd, Hubei Province, China) and Rabbit Glucagon Like Peptide-1 ELISA Kit (Shanghai Huding Biological Technology Co., Shanghai, China) according to the manufacturer’s instructions respectively. Serum oxidative stress related markers Lipid Peroxidation Malondialdehyde (MDA) and 8-hydroxy-2 deoxyguanosine (8-OHdG) were assessed by MDA Assay Kit (Nanjing Jianchen Bioengineering Institute, Jiangsu Province, China) and Rabbit 8-OHdG ELISA Kit (Shanghai Huding Biological Technology Co., Shanghai, China). Serum antioxidant enzyme superoxide Jianchen Bioengineering Institute, Jiangsu Province, China). And the infammation maker high-sensitivity C-reactive protein (hs-CRP) level was detected using Rabbit hs-CRP ELISA KIT (Wuhan Huamei Biological Engineering Co., Ltd, Hubei Province, China).

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